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Dr. Kapil Kumar

Dr. Kapil Kumar

Associate Professor

Profile Summary

Dr. Kapil Kumar received his M.S. (Pharm) and Ph.D. in Medicinal Chemistry from institute of national importance i.e. National Institute of Pharmaceutical Education and Research (NIPER) Mohali, India. He has previously worked in ISF college of pharmacy, Moga, Punjab, Apeejay Stya University Gurugram and Narsee Monjee Institute of Management Studies (NMIMS), Hyderabad at different positions. He has 11 years of teaching and research experience. His research has resulted in the international publication of over 34 peer-reviewed articles of high reputed and indexed in Scopus, the web of science, and PubMed. Seven edited textbooks and one book chapter (Wiley) is also in his credit. He has files various patents. He is in the reviewer panel of many reputed journals of international publishing houses like Elsevier, Wiley, Royal society of chemistry, Bentham science, Taylor and Francis and Springer. Various awards, travel grants and accolades were also received from reputed organizations. He has presented his research work in various national and international conferences.

Work Experience

Dr. Kapil Kumar Joined UPES in January 2024 as Associate Professor at School of Health Sciences and Technology UPES. Before joining UPES, he worked in following organizations:

  • March 2022-January 2024, Associate Professor at Apeejay Stya University, Sohna, Gurugram, Haryana-122103, India.
  • July 2019-March 2022, Assistant Professor at SVKM’s NMIMS, Hyderabad, Telangana-509301, India.
  • Feb, 2017-July 2019, Assistant Professor at Apeejay Stya University, Sohna, Gurgaon, Haryana-122103, India.
  • Aug, 2015-Feb, 2017, Faculty at Indo-Soviet Friendship College of Pharmacy (ISFCP), Moga, Punjab-142001, India

Research Interests

His research interests involve the synthesis of novel molecules of pharmacological interest against cancer, diabetes, metabolic syndrome and infectious diseases. His synthetic expertise is focused on heterocyclic synthesis, methodology development, asymmetric synthesis, green chemistry, total synthesis, computer-aided drug design (CADD), nanoparticle-based synthesis etc.

Awards and Grants

Grants 

  • 2022-Grant of Rs. 17 lac as principle investigator from Haryana State Council for Science, Innovation and Technology (HSCSIT) on title: Waste to best: Conversion of Krishi Avashesh (agriculture waste) to pharmaceutical excipients and their biomedical and technical applications. (PI, 17 lac). 
  • 2022- Grant of Rs. 3.2 lac from Apeejay Stya University, SEED Grant on title: Development of diversified tryptanthrin derivatives as antioxidant agents. (Principle Investigator, 3.2 lac).

Awards 

  1. Selected to attend fully sponsored (Travel, accommodation, registration and food) hands on training program on “Pre-clinical drug screening and characterization of pharmaceuticals” under the scheme of DST-STUTI and organized by L.M. college of pharmacy in association with IIT Gandhinagar from 26th September-02nd October 2022 (7 days). 
  2. Awarded with 2nd prize in oral presentation in a conference organized by Indian Institute of Technology, Guwahati from 23-25th January, 2020 on theme WATER 2020. 
  3. Received NMIMS University travel grant for attending a conference at IIT, Guwahati during 23-25th January, 2020 on theme WATER 2020. (Amount: Rs. 34,000) 
  4. Awarded a certificate for appointment of associate editorial board member of the journal “Current Computer-Aided Drug Design” in Year 2020 (Publisher: Bentham science, Impact Factor: 1.606) 
  5. Awarded a certificate for appointment of associate editorial board member of the journal “Medicinal Chemistry” and working as EBM Since January 2020 (Publisher: Bentham science, Impact Factor: 2.323).

Scholarly Activities

Dr. Kumar’s research endeavours have resulted in numerous publications in high impact journals including European journal of medicinal chemistry, Bioorganic chemistry, Bioorganic and medicinal chemistry, Journal of organic chemistry, RSC advances, Chemistry select, Journal of Heterocyclic chemistry, Toxicology in Vitro, Anticancer agents in medicinal chemistry, Current topics in medicinal chemistry, Medicinal chemistry etc. Dr. Kumar’s scholarly activities exemplify a holistic approach to teaching, research and mentorship. A list of Dr. Kumar’s publications is here: 

  1. Puri, S.; Yadav, T. T.; Chouhan, M.; Kumar, K.* Synthetic and clinical perspectives of EVOTAZ: An overview. Mini Rev. Med. Chem. 2024, 24, 372-390. (Impact Factor: 3.8, Bentham Publication, ISSN: 1389-5575). 
  2. Kumawat, M. K.; Kaur, R.; Kumar, K.* In-silico prediction of novel fused quinazoline based topoisomerase inhibitors as anticancer agents. Med. Chem. 2023, 19, 431-444. (Impact Factor: 2.3, Bentham Publication, ISSN: 1875-6638). 
  3. Puri, S.; Ahmad, I.; Patel, H.; Kumar, K*.; Juvale, K. Evaluation of oxindole derivatives as a potential anticancer agent against breast carcinoma cells: In vitro, in silico and molecular docking study. Toxicol. In Vitro 2023, 86, 105517. (Impact Factor: 3.2, Elsevier, ISSN: 0887-2333). 
  4. Pawar, S.; Kumawat, M. K.; Kundu, M.; Kumar, K.* Synthetic and medicinal perspective of antileishmanial agents: An overview. J. Mol. Struct. 2023, 1271, 133977. (Impact Factor: 3.8, Elsevier, ISSN: 0022-2860). 
  5. Rathod, B.; Kumar, K*. Synthetic and medicinal perspective of 1,2,4-triazole as anticancer agents. Chem. Biodivers. 2022, 19, e202200679. (Impact Factor: 2.9, Wiley, ISSN: 1612-1880). 
  6. Kumar, K.* Microwave assisted diversified synthesis of pyrimidines: An overview. J. Heterocycl. Chem. 2022, 59, 205-238. (Impact Factor: 2.4, Wiley Publication, ISSN: 1943-5193). 
  7. Konar, D.; Maru, S.; Kar, S.; Kumar, K.* Synthesis and clinical development of palbociclib: An overview. Med. Chem. 2022, 18, 2-25. (Impact Factor: 2.3, Bentham Publication, ISSN: 1875-6638). 
  8. Pawar, S.; Kumar, K.; Gupta, M. K.; Rawal, R. K. Synthetic and medicinal perspective of fused-thiazoles as anticancer agents. Anti-Cancer Agents Med. Chem. 2021, 21, 1379-1402. (Impact Factor: 2.8, Bentham Publication, ISSN: 1875-5992). 
  9. Kaur, R.; Kumar, K.* Synthetic and medicinal perspective of quinolines as antiviral agents. Eur. J. Med. Chem. 2021, 215, 113220-113258. (Impact Factor: 6.7, Elsevier, ISSN: 0223-5234). 
  10. Kumar, K.* TosMIC: A powerful synthon for cyclization and sulfonylation. ChemistrySelect 2020, 5, 10298-10328. (Impact Factor: 2.1, Wiley Publication, ISSN: 2365-6549).  
  11. Kumar, K.*; Rawal, R. K. CuI/DBU-mediated MBH reaction of isatins: A convenient synthesis of 3-substituted-3-hydroxy-2-oxindole. ChemistrySelect 2020, 5, 3048-3051. (Impact Factor: 2.1, Wiley Publication, ISSN: 2365-6549).  
  12. Kapoor, Y.; Kumar, K*. Structural and clinical impact of anti-allergy agents: An overview. Bioorg. Chem. 2020, 94, 103351-103375. (Impact Factor: 5.1, Elsevier, ISSN: 0045-2068). 
  13. Manjal, S. K.; Pathania, S.; Bhatia, R.; Kaur, R.; Kumar, K*.; Rawal, R. K. Diversified synthetic strategies for pyrroloindoles: An overview. J. Heterocycl. Chem. 2019, 56, 2318-2332. (Impact Factor: 2.4, Wiley Publication, ISSN:1943-5193). 
  14. Kaur, R.; Kapoor, Y.; Manjal, S. K.; Rawal, R. K.; Kumar, K*. Diversity-oriented synthetic approaches for furoindoline: A review. Curr. Org. Synth. 2019, 16, 342-368. (Impact Factor: 1.8, Bentham, ISSN: 1875-6271).  
  15. Kaur, R.; Kumar, K*. One-pot synthesis of [4-(tert-butyl)-1H-pyrrol-3-yl](phenyl)methanone from tosylmethyl isocyanide and carbonyl compound. Chem. Heterocycl. Compd. 2018, 54, 700-702. (Impact Factor: 1.5, Springer, ISSN: 1573-8353). 
  16. Kaur, R.; Manjal, S. K.; Rawal, R. K.; Kumar, K*. Recent synthetic and medicinal perspective of tryptanthrin. Bioorg. Med. Chem. 2017, 25, 4533-4552. (Impact Factor: 3.5, Elsevier, ISSN: 0968-0896). 
  17. Manjal, S. K.; Kaur, R.; Bhatia, R.; Kumar, K.; Singh, V.; Shankar, R.; Kaur, R.; Rawal, R. K. Synthetic and medicinal perspective of thiazolidinones: A review. Bioorg. Chem. 2017, 75, 406-423. (Impact Factor: 5.1, Elsevier, ISSN: 0045-2068). 
  18. Mittal, M.; Kumar, K.; Anghore, D.; Rawal, R. K. ICP-MS: Analytical method for identification and detection of elemental impurities. Curr. Drug Discover. Tech. 2017, 14, 106-120. (Bentham Publication, ISSN: 1875-6220) 
  19. Kumar, K.; More, S. S.; Khatik, G. L.; Rawal, R. K.; Nair, V. A. A highly stereoselective chiral auxiliary-assisted reductive cyclization to furoindoline. J. Heterocycl. Chem. 2017, 54, 2696-2702. (Impact Factor: 2.4, Wiley Publication, ISSN: 1943-5193). 
  20. Kaur, R.; Choudhry, S.; Kumar, K.; Gupta, M. K.; Rawal, R. K. Recent synthetic and medicinal perspectives of dihydropyrimidinones: a review. Eur. J. Med. Chem. 2017, 132, 108-134. (Impact Factor: 6.7, Elsevier, ISSN: 0223-5234) 
  21. Kumar, B.; Singh, V.; Shankar, R.; Kumar, K.; Rawal, R. K. Synthetic and medicinal prospective of structurally modified curcumins. Curr. Topics. Med. Chem. 2017, 17,148-161. (Impact Factor: 3.4, Bentham, ISSN: 1873-4294). 
  22. Talwan, P.; Choudhary, S.; Kumar, K.; Rawal, R. K. Chemical and medicinal versatility of substituted 1,4-dihydropyridines. Curr. Bioact. Compd. 2017, 13, 109-120. (Bentham, ISSN: 1875-6646).  
  23. Kumar, K.; Konar, D.; Goyal, S.; Gangar, M.; Chouhan, M.; Rawal, R. K.; Nair, V. A. Water promoted regiospecific azidolysis and copper catalysed azide alkyne cycloaddition: One-pot synthesis of 3-hydroxy-1-alkyl-3-[(4-aryl/alkyl-1H-1,2,3-triazol-1-yl)methyl]indolin-2-one derivatives. J. Org. Chem. 2016, 81, 9757-9764. (Impact Factor: 3.6, ACS, ISSN: 0022-3263).  
  24. Kumar, K.; Siddique, J.; Gangar, M.; Goyal, S.; Rawal, R. K.; Nair, V. A. ZrCl4 catalysed diastereoselective synthesis of spirocarbocyclic oxindoles via [4+2] cycloaddition. ChemistrySelect 2016, 1, 2409-2412. (Impact Factor: 2.1, Wiley Publication, ISSN: 2365-6549). 
  25. Kumar, K.; Konar, D.; Goyal, S.; Gangar, M.; Chouhan, M.; Rawal, R. K.; Nair, V. A. AlCl3/Cyclohexane mediated electrophilic activation of isothiocyanates: An efficient synthesis of thioamides. ChemistrySelect 2016, 1, 3228-3231. (Impact Factor: 2.1, Wiley Publication, ISSN: 2365-6549). 
  26. Kumar, K.; More, S. S.; Goyal, S.; Gangar, M.; Khatik, G. L.; Rawal, R. K.; Nair, V. A. A convenient synthesis of 4-alkyl-3-benzyolpyrroles from α,β-unsaturated ketone and tosylmethylisocyanide. Tetrahedron Lett. 2016, 57, 2315-2319. (Impact Factor: 1.8, Elsevier, ISSN: 0040-4039). 
  27. Kumar, K.; Mudshinge, S. R.; Goyal, S., Gangar, M.; Nair, V. A. A catalyst free, one pot approach for the synthesis of quinoxaline derivatives via oxidative cyclization of 1,2-diamines and phenacyl bromides. Tetrahedron Lett. 2015, 56, 1266-1271. (Impact Factor: 1.8, Elsevier, ISSN: 0040-4039). 
  28. Goyal, S.; Patel, J. K.; Gangar, M.; Kumar, K.; Nair, V. A. Zirconocene dichloride catalysed one-pot synthesis of pyrroles through nitroalkene-enamine assembly. RSC Adv. 2015, 5, 3187-3195. (Impact Factor 3.9, Royal Society of Chemistry, ISSN: 2046-2069).  
  29. Goyal, S.; Patel, BK.; Sharma, R.; Chouhan, M.; Kumar, K.; Gangar, M.; Nair, V. A. An efficient strategy for the synthesis of syn 1,3-diols via iterative acetate aldol reactions and synthesis of atorvastatin lactone. Tetrahedron Lett. 2015, 56, 5409-5412. (Impact Factor: 1.8, Elsevier, ISSN: 0040-4039). 
  30. Gangar, M.; Kashyap, N.; Kumar, K.; Goyal, S.; Nair, V. A. Imidazolidinone based chiral auxiliary mediated acetate aldol reactions of isatin derivatives and stereoselective synthesis of 3-substituted-3-hydroxy-2-oxindoles. Tetrahedron Lett. 2015, 56, 7074-7081. (Impact Factor: 1.8, Elsevier, ISSN: 0040-4039). 
  31. Chouhan, M.; Senwar, K. R., Kumar, K.; Sharma, R.; Nair, V. A. Catalytic C-H activation of arylacetylenes: a fast assembly of 3-hydroxy-3-(arylethynyl)indolin-2-ones using CuI/DBU. Synthesis 2014, 46, 2, 195-202. (Impact Factor: 2.6, Thieme Chemistry, ISSN: 0039-7881). 
  32. Kumar, V.; Kumar, K.; Pal, A.; Khatik, G. L.; Nair, V. A. Aldol reactions of 2-thioxotetrahydropyrimidin-4(1H)-ones: stereoregulations from endo- and exo- cyclic chiral centres. Tetrahedron 2013, 69, 1747-1754. (Impact Factor: 2.1, Elsevier, ISSN: 0040-4020).  
  33. Sharma, R.; Kumar, K.; Chouhan, M.; Grover, V.; Nair, V. A. Lithium hydroxide mediated synthesis of 3,4-disubstituted pyrroles.  RSC Adv. 2013, 3, 14521-14527. (Impact Factor 3.9, Royal Society of Chemistry, ISSN: 2046-2069).   
  34. Chouhan, M.; Kumar, K.; Sharma, R.; Grover, V.; Nair, V. A. NiCl2.H2O/NaBH4 in methanol: a mild and efficient strategy for chemoselective deallylation/debenzylation of aryl ethers. Tetrahedron Lett. 2013, 54, 4540-4543. (Impact Factor: 1.8, Elsevier, ISSN: 0040-4039). 

Teaching Philosophy

Dr. Kapil believes in active learning approach. A successful teaching method inspires students to learn, analyze and make them ready for future challenges in life. He believes every student has unique strengths to learn and grow. He teach by involving students by using interactive sessions, blended learning, group discussions and gamification approaches. His teaching philosophy is to build students strength and make them innovative.

Courses Taught

  • B. Pharm.: Pharmaceutical Organic Chemistry-I, II and III
  • Pharmaceutical Analysis-I and Medicinal Chemistry-II, III
  • M. Pharm.: Advanced Organic Chemistry, Advanced Spectroscopic Techniques, Modern Analytical Technique and Medicinal Chemistry 

Contact

kapil.kumar@ddn.upes.ac.in